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Wiley Open Access, Journal of Diabetes Investigation, 6(1), p. 242-251, 2010

DOI: 10.1111/j.2040-1124.2010.00051.x

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Tracing phenotypic reversibility of pancreatic β‐cells in vitro

Journal article published in 2010 by Kohtaro Minami ORCID, Kazumasa Miyawaki, Manami Hara, Shuichi Yamada, Susumu Seino
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Aims/Introduction:  Studies have suggested that pancreatic β‐cells undergo dedifferentiation during proliferation in vitro. However, due to limitations of the methodologies used, the question remains whether such dedifferentiated cells can redifferentiate into β‐cells.