Published in

American Society of Hematology, Blood, 19(123), p. 2968-2977, 2014

DOI: 10.1182/blood-2013-11-539643

Links

Tools

Export citation

Search in Google Scholar

Runx1 and Cbfβ regulate the development of Flt3+ dendritic cell progenitors and restrict myeloproliferative disorder

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

Full text: Download

Red circle
Preprint: archiving forbidden
Orange circle
Postprint: archiving restricted
Red circle
Published version: archiving forbidden
Data provided by SHERPA/RoMEO

Abstract

Key PointsRunx proteins and Cbfβ are required for the development of dendritic cells, which can be rescued by Irf8. Pan-hematopoietic Cbfb-deficient mice develop a myeloproliferative disease and severe anemia and die at 3 to 4 months of age.