Background: Systematic reviews provide critical exploration, evaluation, and synthesis of the unmanageable amount of information and separate the insignificant, unsound, or redundant deadwood in the medical literature from the salient and critical studies that are worthy of reflection. They have been regarded as the highest quality of evidence for clinical practice. Objectives: The National Health Research Institutes of Taiwan provided a series of education for postgraduate health professionals to learn systematic reviews. The curricula of the two-day workshop include how to perform meta-analysis by using RevMan 5. The aim of this study is to investigate the effectiveness of this training program. Methods: A pre- and post-survey of participants was carried out to examine views related to systematic reviews including changes in beliefs, attitudes, knowledge, skills, and perceived barriers. Results: The professions of participants include physicians, nurses, pharmacists, nutritionists, and public health experts. After educational training, participants’ knowledge and skill in the systematic reviews significantly increase (p