Published in
American Society of Hematology, Blood, 5(128), p. 680-685, 2016
DOI: 10.1182/blood-2016-03-705780
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- American Society of Hematology | PDF
- [www.ncbi.nlm.nih.gov] | PDF
- [europepmc.org] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
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Immunoregulatory roles of versican proteolysis in the myeloma microenvironment
Journal article published in 2016 by
Chelsea Hope,
Simon Foulcer,
Justin Jagodinsky 
,
Sarah X. Chen,
Jeffrey L. Jensen,
Sanjay Patel,
Catherine Leith,
Ioanna Maroulakou,
Natalie Callander,
Shigeki Miyamoto,
Peiman Hematti,
Suneel S. Apte,
Fotis Asimakopoulos
,
Sarah X. Chen,
Jeffrey L. Jensen,
Sanjay Patel,
Catherine Leith,
Ioanna Maroulakou,
Natalie Callander,
Shigeki Miyamoto,
Peiman Hematti,
Suneel S. Apte,
Fotis Asimakopoulos
This paper is made freely available by the publisher.
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Abstract
Key Points Interplay between myeloma niche stromal cells and myeloid cells generates versikine, a novel damage-associated molecular pattern. Versikine may promote antigen-presenting cell maturation and CD8+ T-cell activation/recruitment to the tumor bed.