Published in
American Society of Hematology, Blood, 2(131), p. 247-262
DOI: 10.1182/blood-2017-05-780668
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NK cell recovery after haploidentical HSCT with posttransplant cyclophosphamide: dynamics and clinical implications
Journal article published in 2017 by
Antonio Russo,
Giacomo Oliveira 
,
Sofia Berglund,
Raffaella Greco,
Valentina Gambacorta,
Nicoletta Cieri ,
Cristina Toffalori,
Laura Zito,
Francesca Lorentino,
Simona Piemontese,
Mara Morelli,
Fabio Giglio,
Andrea Assanelli,
Maria Teresa Lupo Stanghellini ,
Chiara Bonini
and other authors.
,
Sofia Berglund,
Raffaella Greco,
Valentina Gambacorta,
Nicoletta Cieri ,
Cristina Toffalori,
Laura Zito,
Francesca Lorentino,
Simona Piemontese,
Mara Morelli,
Fabio Giglio,
Andrea Assanelli,
Maria Teresa Lupo Stanghellini ,
Chiara Bonini
and other authors.
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Abstract
Key Points Posttransplantation cyclophosphamide eliminates most mature donor NK cells infused with the graft, including alloreactive NK cells. High levels of serum interleukin-15 early after HSCT provide a favorable environment for adoptive infusion of mature donor NK cells.