Published in

Wiley, Clinical Genetics, 2(75), p. 101-106, 2009

DOI: 10.1111/j.1399-0004.2008.01083.x

Links

Tools

Export citation

Search in Google Scholar

Finding genes underlying human disease

Journal article published in 2009 by Cm M. Stein ORCID, Rc C. Elston
This paper is available in a repository.
This paper is available in a repository.

Full text: Download

Green circle
Preprint: archiving allowed
Upload
Orange circle
Postprint: archiving restricted
Upload
Red circle
Published version: archiving forbidden
Policy details
Data provided by SHERPA/RoMEO

Abstract

With the surge in genome-wide association studies (GWAS), many have asked the question ‘Are linkage studies dead?’ In this article, we survey the approaches used in mapping human disease genes, reviewing the analysis strategies that preceded and laid the groundwork for GWAS. We note that earlier approaches are still useful and the development of new methodology is warranted.