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MyJove Corporation, Journal of Visualized Experiments, 39, 2010

DOI: 10.3791/2056-v

MyJove Corporation, Journal of Visualized Experiments, 39

DOI: 10.3791/2056

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How to Culture, Record and Stimulate Neuronal Networks on Micro-electrode Arrays (MEAs)

Journal article published in 2010 by Chadwick M. Hales, John D. Rolston ORCID, Steve M. Potter
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

For the last century, many neuroscientists around the world have dedicated their lives to understanding how neuronal networks work and why they stop working in various diseases. Studies have included neuropathological observation, fluorescent microscopy with genetic labeling, and intracellular recording in both dissociated neurons and slice preparations. This protocol discusses another technology, which involves growing dissociated neuronal cultures on micro-electrode arrays (also called multi-electrode arrays, MEAs).