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Nature Research, Nature Immunology, 11(9), p. 1210-1212, 2008

DOI: 10.1038/ni1108-1210

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IFN-γ and self-absorbed CD4+ T cells: a regulatory double negative

Journal article published in 2008 by David Hildeman ORCID, Edith Janssen
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Interferon-γ exerts many effects on the immune system. A new report shows that it induces both autophagy and Irgm1, a GTPase that protects activated CD4+ T cells from executing autophagy.