Published in
American Society for Microbiology, Infection and Immunity, 9(86), 2018
DOI: 10.1128/iai.00244-18
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The Protozoan Parasite Toxoplasma gondii Selectively Reprograms the Host Cell Translatome
Journal article published in 2018 by
Louis-Philippe Leroux 
,
Julie Lorent,
Tyson E. Graber,
Visnu Chaparro ,
Laia Masvidal,
Maria Aguirre,
Bruno D. Fonseca,
Léon C. van Kempen ,
Tommy Alain,
Ola Larsson,
Maritza Jaramillo
,
Julie Lorent,
Tyson E. Graber,
Visnu Chaparro ,
Laia Masvidal,
Maria Aguirre,
Bruno D. Fonseca,
Léon C. van Kempen ,
Tommy Alain,
Ola Larsson,
Maritza Jaramillo
This paper is made freely available by the publisher.
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Abstract
The intracellular parasite Toxoplasma gondii promotes infection by targeting multiple host cell processes; however, whether it modulates mRNA translation is currently unknown. Here, we show that infection of primary murine macrophages with type I or II T. gondii strains causes a profound perturbation of the host cell translatome.