Published in
American Society of Hematology, Blood, 12(130), p. 1441-1444, 2017
DOI: 10.1182/blood-2017-03-774364
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DARC extracellular domain remodeling in maturating reticulocytes explains Plasmodium vivax tropism
Journal article published in 2017 by
Elina Ovchynnikova,
Francesca Aglialoro,
Arthur E. H. Bentlage,
Gestur Vidarsson,
Nichole D. Salinas,
Marieke von Lindern 
,
Niraj H. Tolia,
Emile van den Akker
,
Niraj H. Tolia,
Emile van den Akker
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Abstract
Key PointsP vivax Duffy binding protein associates exclusively with a small population of immature reticulocytes. Increased DARC-DBP binding site accessibility in immature reticulocytes compared with erythrocytes is a key to infection by P vivax.