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American Association for the Advancement of Science, Science Translational Medicine, 436(10), 2018

DOI: 10.1126/scitranslmed.aao3003

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Dual inhibition of MDMX and MDM2 as a therapeutic strategy in leukemia

This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Dual inhibition of MDMX and MDM2 by an α-helical p53-stapled peptide (ALRN-6924) results in robust antitumor activity in acute myeloid leukemia.