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Royal Society of Chemistry, RSC Advances, 64(6), p. 58884-58889, 2016

DOI: 10.1039/c6ra12875k

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β-Alanyl aminopeptidase-activated fluorogenic probes for the rapid identification of Pseudomonas aeruginosa in clinical samples

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

The fluorogenic self-immolative substrates8are specifically hydrolyzed by β-alanyl aminopeptidase, resulting in a 1,6-elimination and the release of the highly fluorescent hydroxycoumarins6.