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Oxford University Press, Clinical Infectious Diseases, 8(68), p. 1413-1419, 2018

DOI: 10.1093/cid/ciy675

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Laboratory-acquired Scrub Typhus and Murine Typhus Infections: The Argument for a Risk-based Approach to Biosafety Requirements for Orientia tsutsugamushi and Rickettsia typhi Laboratory Activities

Journal article published in 2018 by Stuart D. Blacksell ORCID, Matthew T. Robinson ORCID, Paul N. Newton, Nicholas P. J. Day
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

The highest-risk activities for scrub/murine typhus laboratory-acquired infections were working with infectious laboratory animals. Eight scrub typhus deaths occurred during the preantibiotic era. Risk-based biosafety approaches would improve efficiencies of in vitro/in vivo growth of scrub/murine typhus.