Published in

National Academy of Sciences, Proceedings of the National Academy of Sciences, 28(115), p. 7440-7445, 2018

DOI: 10.1073/pnas.1718891115

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Dissecting the neurofunctional bases of intentional action

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Data provided by SHERPA/RoMEO

Abstract

Significance We provide evidence that our intentions can be fragmented in various components subserved by partially dissociable neural circuits. We found that the decision of what to do, when to do it, and whether to do it depends on separable systems that go beyond the mesial prefrontal wall of previous proposals, involving cortical and subcortical brain regions in a component-specific manner. In addition, we found that deciding whether to act or not requires strong interhemispheric interactions of the frontal lobes. This explicit evidence of dissociable neural foundations of intentional actions will guide the exploration of brain disorders of specific components of intentionality.