Published in
American Association for the Advancement of Science, Science Signaling, 464(10), 2017
DOI: 10.1126/scisignal.aag3209
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PDZRN3 destabilizes endothelial cell-cell junctions through a PKCζ-containing polarity complex to increase vascular permeability
Journal article published in 2017 by
Raj N. Sewduth,
Héléna Kovacic,
Béatrice Jaspard-Vinassa,
Vincent Jecko,
Thomas Wavasseur,
Nicolas Fritsch,
Mathieu Pernot,
Sylvie Jeaningros,
Etienne Roux,
Pascale Dufourcq,
Thierry Couffinhal,
Cécile Duplàa 
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Abstract
Inhibiting the E3 ubiquitin ligase PDZRN3 could stabilize endothelial cell connections to prevent vascular leakage.