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American Society for Microbiology, Antimicrobial Agents and Chemotherapy, 2(61), 2017

DOI: 10.1128/aac.02229-16

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IncP Plasmid Carrying Colistin Resistance Gene mcr-1 in Klebsiella pneumoniae from Hospital Sewage

Journal article published in 2017 by Feifei Zhao, Yu Feng, Xiaoju Lü, Alan McNally, Zhiyong Zong ORCID
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

ABSTRACT A Klebsiella pneumoniae strain of sequence type 313 (ST313) recovered from hospital sewage was found carrying the plasmid-borne colistin resistance gene mcr-1 , which was bracketed by two copies of the insertion sequence IS Apl1 on a 57-kb self-transmissible IncP-type plasmid of a new IncP-1 clade. The carriage of mcr-1 on a self-transmissible broad-host-range plasmid highlights that mcr-1 has the potential to spread beyond the Enterobacteriaceae family.