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Slower CD4 cell decline following cessation of a 3 month course of HAART in primary HIV infection: findings from an observational cohort.
Journal article published in 2007 by
Sarah Fidler,
Julie Fox,
Giota Touloumi,
Nikos Pantazis 
,
Kholoud Porter,
Abdel Babiker,
Jonathan Weber
,
Kholoud Porter,
Abdel Babiker,
Jonathan Weber
Abstract
OBJECTIVE: To investigate the effect of a short course of HAART during primary HIV infection (PHI) on rate of CD4 cell and viral load change. METHODS: Data following HAART cessation from 89 individuals (seroconverting 1999-2003) who chose to take a 3 month course of HAART at PHI were compared with 179 untreated controls in CASCADE, using linear and nonlinear random effects models. Participants were non-randomized but frequency matched for age, sex, risk factor, year of seroconversion and presentation within the first 6 months of seroconversion. Time to CD4 cell count