Public Library of Science, PLoS ONE, 4(10), p. e0124670, 2015
DOI: 10.1371/journal.pone.0124670
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Sirtuin 1 (SIRT1) and sirtuin 2 (SIRT2) are NAD+-dependent protein deacetylases involved in the regulation of key cancer-associated genes. In this study we evaluated the relevance of these deacetylases in lung cancer biology.