American Society of Hematology, Blood, p. blood-2018-05-852566
DOI: 10.1182/blood-2018-05-852566
Full text: Unavailable
Key Points The DNA glycosylase MBD4 acts as a safeguard against damage from 5mC deamination. Germ line MBD4 deficiency stimulates clonal hematopoiesis and guides the development of leukemia via recurrent mutations in DNMT3A.