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American Society for Microbiology, Antimicrobial Agents and Chemotherapy, 8(62), 2018

DOI: 10.1128/aac.00766-18

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Orally Efficacious Broad-Spectrum Ribonucleoside Analog Inhibitor of Influenza and Respiratory Syncytial Viruses

Journal article published in 2018 by Jeong-Joong Yoon, Mart Toots, Sujin Lee, Myung-Eun Lee, Barbara Ludeke, Jasmina M. Luczo, Ketaki Ganti, Robert M. Cox, Zachary M. Sticher, Vindya Edpuganti, Deborah G. Mitchell, Mark A. Lockwood, Alexander A. Kolykhalov, Alexander L. Greninger, Martin L. Moore and other authors.
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Morbidity and mortality resulting from influenza-like disease are a threat, especially for older adults. To improve case management, next-generation broad-spectrum antiviral therapeutics that are efficacious against major drivers of influenza-like disease, including influenza viruses and respiratory syncytial virus (RSV), are urgently needed.