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American Association for the Advancement of Science, Science, 6349(357), 2017

DOI: 10.1126/science.aan3377

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Reconfiguration of DNA molecular arrays driven by information relay

Journal article published in 2017 by Jie Song ORCID, Zhe Li ORCID, Pengfei Wang ORCID, Travis Meyer ORCID, Chengde Mao ORCID, Yonggang Ke ORCID
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Relaying information on DNA tiles Arrays of modular DNA units can relay information by transforming their internal shape in response to binding of DNA trigger strands. Song et al. synthesized rectangular arrays of double-stranded DNA (see the Perspective by Yang and Lin). Transient square configurations transform into two stable rectangular structures by pinching across a pair of opposing vertices. Binding of DNA trigger strands causes switching into the alternative stable configuration. The tiles thus create a cascade of transformations along a particular pathway, thereby transmitting information about where binding occurred. Science , this issue p. eaan3377 ; see also p. 352