Published in
American Society for Microbiology, Infection and Immunity, 10(86), 2018
DOI: 10.1128/iai.00331-18
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Genome plasticity of agr-defective Staphylococcus aureus during clinical infection
Journal article published in 2018 by
Deena R. Altman 
,
Mitchell J. Sullivan,
Kieran I. Chacko,
Divya Balasubramanian,
Theodore R. Pak ,
William E. Sause,
Krishan Kumar,
Robert Sebra,
Gintaras Deikus,
Oliver Attie,
Hannah Rose,
Martha Lewis,
Yi Fulmer,
Ali Bashir,
Andrew Kasarskis
and other authors.
,
Mitchell J. Sullivan,
Kieran I. Chacko,
Divya Balasubramanian,
Theodore R. Pak ,
William E. Sause,
Krishan Kumar,
Robert Sebra,
Gintaras Deikus,
Oliver Attie,
Hannah Rose,
Martha Lewis,
Yi Fulmer,
Ali Bashir,
Andrew Kasarskis
and other authors.
This paper was not found in any repository, but could be made available legally by the author.
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Abstract
Therapy for bacteremia caused by Staphylococcus aureus is often ineffective, even when treatment conditions are optimal according to experimental protocols. Adapted subclones, such as those bearing mutations that attenuate agr -mediated virulence activation, are associated with persistent infection and patient mortality.