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American Society of Hematology, Blood Advances, 5(2), p. 462-469, 2018

DOI: 10.1182/bloodadvances.2017014126

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CDA as a predictive marker for life-threatening toxicities in patients with AML treated with cytarabine

Journal article published in 2018 by Raphaelle Fanciullino, Laure Farnault, Mélanie Donnette, Diane-Charlotte Imbs, Catherine Roche, Geoffroy Venton, Yael Berda-Haddad, Vadim Ivanov, Joseph Ciccolini, L’Houcine Ouafik ORCID, Bruno Lacarelle, Regis Costello
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Key Points Ara-C is the mainstay of treatment for patients with AML, and life-threatening toxicities are common. We demonstrated that cytidine deaminase downregulation predicts severe/lethal toxicities with cytarabine.