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Cell Press, Cell Metabolism, 2(19), p. 175-176, 2014

DOI: 10.1016/j.cmet.2014.01.009

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High Density Lipoproteins Put Out the Fire

Journal article published in 2014 by Kathryn J. Moore ORCID, Edward A. Fisher ORCID
This paper is available in a repository.
This paper is available in a repository.

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Abstract

Macrophages in atherosclerotic plaques are activated, inflammatory cells that directly contribute to the disease process. De Nardo et al. (2013), now report that high density lipoproteins (HDL) can re-program macrophages to be less inflammatory through an ATF-3-dependent pathway, providing another mechanistic basis for the athero-protective properties of HDL.