Published in
American Society of Hematology, Blood, 5(130), p. 606-618
DOI: 10.1182/blood-2016-08-732636
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NY-ESO-1 TCR single edited stem and central memory T cells to treat multiple myeloma without graft-versus-host disease
Journal article published in 2017 by
Sara Mastaglio,
Pietro Genovese 
,
Zulma Magnani,
Eliana Ruggiero,
Elisa Landoni,
Barbara Camisa,
Giulia Schiroli,
Elena Provasi,
Angelo Lombardo,
Andreas Reik,
Nicoletta Cieri ,
Martina Rocchi,
Giacomo Oliveira ,
Giulia Escobar,
Monica Casucci
and other authors.
,
Zulma Magnani,
Eliana Ruggiero,
Elisa Landoni,
Barbara Camisa,
Giulia Schiroli,
Elena Provasi,
Angelo Lombardo,
Andreas Reik,
Nicoletta Cieri ,
Martina Rocchi,
Giacomo Oliveira ,
Giulia Escobar,
Monica Casucci
and other authors.
Distributing this paper is prohibited by the publisher
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Abstract
Key Points TCR SE is a clinically feasible approach to rapidly produce highly performing and specific tumor reactive T cells. NY-ESO-1 TCR SE T cells kill multiple myeloma in the absence of off-target reactivity including alloreactivity.