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Oxford University Press, Bioinformatics, 13(33), p. 2032-2033, 2017

DOI: 10.1093/bioinformatics/btx117

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SVPV: a structural variant prediction viewer for paired-end sequencing datasets

Journal article published in 2017 by Jacob E. Munro ORCID, Sally L. Dunwoodie, Eleni Giannoulatou
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Data provided by SHERPA/RoMEO

Abstract

Abstract Motivation A wide range of algorithms exist for the prediction of structural variants (SVs) from paired-end whole genome sequencing (WGS) alignments. It is essential for the purpose of quality control to be able to visualize, compare and contrast the data underlying the predictions across multiple different algorithms. Results We provide the structural variant prediction viewer, a tool which presents a visual summary of the most relevant features for SV prediction from WGS data. SV calls from multiple prediction algorithms may be visualized together, along with annotation of population allele frequencies from reference SV datasets. Gene annotations may also be included. The application is capable of running in a Graphical User Interface (GUI) mode for visualizing SVs one by one, or in batch mode for processing many SVs serially. Availability and Implementation SVPV is available at GitHub (https://github.com/VCCRI/SVPV/). Supplementary information Supplementary data are available at Bioinformatics online.