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American Society of Hematology, Blood, 4(130), p. 514-526, 2017

DOI: 10.1182/blood-2017-02-770149

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KRASG12D expression in lung-resident myeloid cells promotes pulmonary LCH-like neoplasm sensitive to statin treatment

Journal article published in 2017 by Tamihiro Kamata, Susan Giblett, Catrin Pritchard ORCID
Distributing this paper is prohibited by the publisher
Distributing this paper is prohibited by the publisher

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Abstract

Key PointsKRASG12D expression in mouse lung myeloid cells induces pulmonary LCH-like neoplasms. KRASG12D-induced LCH-like neoplasms are sensitive to in vivo treatment with 3-hydroxy-3-methylglutaryl coenzyme A inhibitor atorvastatin.