Published in
American Society of Hematology, Blood Advances, 2(2), p. 126-141, 2018
DOI: 10.1182/bloodadvances.2017011072
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Immune rebound associates with a favorable clinical response to autologous HSCT in systemic sclerosis patients
Journal article published in 2018 by
Lucas C. M. Arruda 
,
Kelen C. R. Malmegrim ,
João R. Lima-Júnior,
Emmanuel Clave,
Juliana B. E. Dias,
Daniela A. Moraes,
Corinne Douay,
Isabelle Fournier,
Hélène Moins-Teisserenc ,
Antônio José Alberdi,
Dimas T. Covas,
Belinda P. Simões,
Pauline Lansiaux,
Antoine Toubert ,
Maria Carolina Oliveira
,
Kelen C. R. Malmegrim ,
João R. Lima-Júnior,
Emmanuel Clave,
Juliana B. E. Dias,
Daniela A. Moraes,
Corinne Douay,
Isabelle Fournier,
Hélène Moins-Teisserenc ,
Antônio José Alberdi,
Dimas T. Covas,
Belinda P. Simões,
Pauline Lansiaux,
Antoine Toubert ,
Maria Carolina Oliveira
This paper is made freely available by the publisher.
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Abstract
Key Points Clinical response of SSc patients after AHSCT is associated with thymic and bone marrow rebounds. Responder patients showed higher Treg and Breg counts and lower pre-/post-AHSCT TCR repertoire overlap than nonresponder patients.