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American Association for the Advancement of Science, Science Translational Medicine, 348(8), 2016

DOI: 10.1126/scitranslmed.aac4976

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Smad7 gene delivery prevents muscle wasting associated with cancer cachexia in mice

This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Muscle-directed Smad7 gene delivery prevents the loss of skeletal muscle mass and strength in mouse models of cachexia, an important contributor to poor prognosis in patients with advanced cancer.