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Elsevier, Journal of Allergy and Clinical Immunology, 1(128), p. 212-214, 2011

DOI: 10.1016/j.jaci.2011.02.035

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Diacylglycerol kinase ζ deficiency in a non-CD4+ T-cell compartment leads to increased peanut hypersensitivity

Journal article published in 2011 by Mike Kulis, Chi-Keung Wan ORCID, Balachandra K. Gorentla, A. Wesley Burks, Xiao-Ping Zhong
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Peanut sensitization in diacylglycerol kinase zeta (DGKζ) deficient mice led to elevated peanut-IgE levels and severe anaphylaxis. DGKζ deficient CD4+T cells did not account for the phenotype. Future studies will determine which immune lineage caused increased food hypersensitivity.