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Royal Society of Chemistry, RSC Advances, 39(8), p. 21985-21992, 2018

DOI: 10.1039/c8ra01309h

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Microbial transformation of mestanolone byMacrophomina phaseolinaandCunninghamella blakesleeanaand anticancer activities of the transformed products

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

The microbial transformation of anabolic androgenic steroid mestanolone (1) withMacrophomina phaseolinaandCunninghamella blakesleeanahas afforded seven metabolites. Some of them have exhibited moderate cytotoxicity against HeLa cancer cell line.