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Oxford University Press (OUP), The Journal of Infectious Diseases, 2(210), p. 171-182

DOI: 10.1093/infdis/jiu037

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Antibiotic Treatment Suppresses Rotavirus Infection and Enhances Specific Humoral Immunity

Journal article published in 2014 by Robin Uchiyama, Benoit Chassaing ORCID, Benyue Zhang, Andrew T. Gewirtz
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Background. Rotavirus causes 500 000 deaths and millions of physician visits and hospitalizations per year, with worse outcomes and reduced vaccine efficacy in developing countries. We hypothesized that the gut microbiota might modulate rotavirus infection and/or antibody response and thus potentially play a role in such regional differences.