Published in
Oxford University Press, Metallomics, 5(10), p. 679-695, 2018
DOI: 10.1039/c7mt00348j
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Human Mn-superoxide dismutase inactivation by peroxynitrite: a paradigm of metal-catalyzed tyrosine nitrationin vitroandin vivo
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Abstract
Nitration of human MnSOD at active site Tyr34 represents a biologically-relevant oxidative post-translational modification that causes enzyme inactivation.