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Royal Society of Chemistry, Chemical Science, 4(9), p. 896-903, 2018

DOI: 10.1039/c7sc02736b

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Peptide nucleic acid-templated selenocystine–selenoester ligation enables rapid miRNA detection

Journal article published in 2018 by Jessica Sayers ORCID, Richard J. Payne ORCID, Nicolas Winssinger ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

A PNA-templated peptide ligation reaction has been developed between selenocystine and selenoesters. The methodology was used for the sequence specific detection of miRNA at low concentrations.