Published in
Royal Society of Chemistry, RSC Advances, 4(8), p. 2219-2228, 2018
DOI: 10.1039/c7ra11713b
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G<sub>s</sub>protein peptidomimetics as allosteric modulators of the β<sub>2</sub>-adrenergic receptor
Journal article published in 2018 by
Lotte-Emilie Boyhus,
Mia Danielsen 
,
Nina Smidt Bengtson,
Micha Ben Achim Kunze,
Xavier Kubiak,
Tjerk J. Sminia,
Jacob Hartvig Løper,
Phuong Thu Tran,
Kresten Lindorff-Larsen ,
Søren G. F. Rasmussen,
Jesper Mosolff Mathiesen ,
Daniel Sejer Pedersen
,
Nina Smidt Bengtson,
Micha Ben Achim Kunze,
Xavier Kubiak,
Tjerk J. Sminia,
Jacob Hartvig Løper,
Phuong Thu Tran,
Kresten Lindorff-Larsen ,
Søren G. F. Rasmussen,
Jesper Mosolff Mathiesen ,
Daniel Sejer Pedersen
This paper is made freely available by the publisher.
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Abstract
A series of Gsprotein peptidomimetics were designed and synthesised based on the published X-ray crystal structure of the active state β2-adrenergic receptor (β2AR) in complex with the Gsprotein (PDB 3SN6).