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Hindawi, Surgery Research and Practice, (2014), p. 1-4, 2014

DOI: 10.1155/2014/731481

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Nonfunctional Metastatic Parathyroid Carcinoma in the Setting of Multiple Endocrine Neoplasia Type 2A Syndrome

Journal article published in 2014 by María Posada-González, Joaquín Gómez-Ramírez, Manuel Luque-Ramírez ORCID, Mercedes Guijarro, Elena Martín-Pérez, Ana Rodríguez-Sánchez, Iñigo García-Sanz, Eduardo Larrañaga
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Parathyroid carcinoma is a very rare malignancy. It has been associated with hyperparathyroidism-jaw tumour syndrome, familial isolated primary hyperparathyroidism, and multiple endocrine neoplasia type 1 (MEN-1) and 2A (MEN-2A) syndromes. We report a 54-year-old man with a MEN-2A which presents with a nonfunctional metastatic parathyroid carcinoma and a pheochromocytoma in the absence of medullary thyroid carcinoma. Only a few cases of parathyroid carcinoma have been reported in the literature associated with this syndrome.