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F1000Research, F1000Research, (9), p. 213, 2020

DOI: 10.12688/f1000research.22242.1

F1000Research, F1000Research, (9), p. 213, 2020

DOI: 10.12688/f1000research.22242.2

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AlignmentViewer: Sequence Analysis of Large Protein Families

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Postprint: archiving forbidden
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Data provided by SHERPA/RoMEO

Abstract

AlignmentViewer is a web-based tool to view and analyze multiple sequence alignments of protein families. The particular strengths of AlignmentViewer include flexible visualization at different scales as well as analysis of conservation patterns and of the distribution of proteins in sequence space. The tool is directly accessible in web browsers without the need for software installation. It can handle protein families with tens of thousands of sequences and is particularly suitable for evolutionary coupling analysis, e.g. via EVcouplings.org.