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BioMed Central, Genome Biology, 1(16), 2015

DOI: 10.1186/s13059-015-0744-8

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Filling the gap: Micro-C accesses the nucleosomal fiber at 100–1000 bp resolution

Journal article published in 2015 by Julien Mozziconacci, Romain Koszul ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Abstract The fine three-dimensional structure of the nucleosomal fiber has remained elusive to genome-wide chromosome conformation capture (3C) approaches. A new study mapping contacts at the single nucleosome level (Micro-C) reveals topological interacting domains along budding yeast chromosomes. These domains encompass one to five consecutive genes and are delimited by highly active promoters.