Dissemin is shutting down on January 1st, 2025

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Public Library of Science, PLoS ONE, 4(9), p. e93559, 2014

DOI: 10.1371/journal.pone.0093559

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Model-Based Analysis of Costs and Outcomes of Non-Invasive Prenatal Testing for Down’s Syndrome Using Cell Free Fetal DNA in the UK National Health Service

Journal article published in 2014 by Stephen Morris, Saffron Karlsen, Nancy Chung, Melissa Hill, Lyn S. Chitty ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Non-invasive prenatal testing (NIPT) for Down's syndrome (DS) using cell free fetal DNA in maternal blood has the potential to dramatically alter the way prenatal screening and diagnosis is delivered. Before NIPT can be implemented into routine practice, information is required on its costs and benefits. We investigated the costs and outcomes of NIPT for DS as contingent testing and as first-line testing compared with the current DS screening programme in the UK National Health Service.