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American Society for Microbiology, Journal of Bacteriology, 1(178), p. 309-313, 1996

DOI: 10.1128/jb.178.1.309-313.1996

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Differentially transcribed regions of Haloferax volcanii genome depending on the medium salinity.

Journal article published in 1996 by C. Ferrer, F. J. M. Mojica, G. Juez, F. Rodríguez-Valera ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

To identify genomic regions involved in osmoregulation in the extremely halophilic archaeon Haloferax volcanii, we used a technique which involves hybridization of cDNAs obtained at different salinities against a cosmid library of the organism. Both low and high salt concentrations trigger differential expression; however, adaptation to low salinities seems to elicit a wider response. The presence of a large domain within the largest of the megaplasmids with a strong response to low salt concentrations is noteworthy.