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American Chemical Society, Nano Letters, 3(10), p. 782-787, 2010

DOI: 10.1021/nl902675h

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Fifteen-Piconewton Force Detection from Neural Growth Cones Using Nanowire Arrays

Journal article published in 2010 by Waldemar Hällström, Waldemar Hällström, Monica Lexholm, Dmitry B. Suyatin, Greger Hammarin ORCID, Dan Hessman, Lars Samuelson, Lars Montelius, Martin Kanje, Christelle N. Prinz
This paper was not found in any repository; the policy of its publisher is unknown or unclear.
This paper was not found in any repository; the policy of its publisher is unknown or unclear.

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Abstract

We used epitaxially grown monodisperse nanowire arrays to measure cellular forces with a spatial resolution of 1 mu m. Nerve cells were cultured on the array and cellular forces were calculated from the displacement of the nanowire tips. The measurements were done in situ on live cells using confocal microscopy, Forces down to 15 pN were measured on neural growth cones, showing that this method can be used to study the Fine details of growth-cone dynamics.