Published in

International Union of Crystallography, Acta Crystallographica Section E: Structure Reports Online, 4(68), p. o1263-o1263, 2012

DOI: 10.1107/s1600536812013207

Links

Tools

Export citation

Search in Google Scholar

6-Methyl­ideneandrost-4-ene-3,17-dione

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

Full text: Download

Green circle
Preprint: archiving allowed
Green circle
Postprint: archiving allowed
Red circle
Published version: archiving forbidden
Data provided by SHERPA/RoMEO

Abstract

In the title compound, C20H26O2, which is the 6-methylene derivative of androstenedione and a synthetic percursor of exemestane, the steroidAring approximates to a sofa (or envelope) conformation, with the methylene group adjacent to the link to theBring lying out of the plane of the other atoms. TheBandCrings have slightly flattened chair conformations and theDring is an envelope, with the CH group forming the flap. In the crystal, molecules are linked by two distinct C—H...O hydrogen bonds, involving acidic H atoms close to C=C and C=O double bonds.