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Taylor and Francis Group, Communicative and Integrative Biology, 2(5), p. 199-202

DOI: 10.4161/cib.18892

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Evolutionary routes from a prebiotic ANA-world

Journal article published in 2012 by Sebastian Braun, Christine Humphreys, Trevor Clive Dale ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Recent experimental support has been generated for a model of prebiotic development that postulates a role for Amyloid-Nucleic Acid (ANA)-fibers as the earliest replicating entities capable of undergoing Darwinian evolution. Here, this new model is compared with existing RNA-world models with a particular focus on trajectories that lead to evolutionary-beneficial interactions between nucleic acid, protein and lipid components. This analysis suggests a number of new areas for fruitful experimental studies.