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Wiley, Medical Physics, 9(40), p. 092503, 2013

DOI: 10.1118/1.4816944

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Fast direct estimation of the blood input function and myocardial time activity curve from dynamic SPECT projections via reduction in spatial and temporal dimensions

Journal article published in 2013 by Yunlong Zan, Rostyslav Boutchko, Qiu Huang, Biao Li, Kewei Chen ORCID, Grant T. Gullberg
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Purpose: Reconstruction of parametric images from dynamic single photon emission computed tomography (SPECT) data acquired with slow rotating cameras is a challenge because the estimation of the time–activity curves (TACs) may involve fitting data to an inconsistent underdetermined system of equations. This work presents a novel algorithm for the estimation of the blood input function and myocardial TAC with high accuracy and high efficiency directly from these projections.