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American Heart Association, Stroke, 4(38), p. 1380-1383, 2007

DOI: 10.1161/01.str.0000260089.17105.27

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Admission facility is associated with outcome of basilar artery occlusion.

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Background and Purpose— Basilar artery occlusion (BAO) is a stroke subtype with poor prognosis, but recanalizing therapies have been reported to be effective. We investigated whether initial admission to telemedically linked general hospitals with subsequent stroke-center transfer is related to poorer outcome than direct admission to stroke centers. Methods— All BAO cases of 3 stroke centers in Munich and 1 center in Regensburg between March 1, 2003 and December 31, 2004 were included, either if patients were directly admitted to stroke centers (n=23) or had initial admission to general hospitals of the telemedical network for integrative stroke care (TEMPiS) and secondary transfer to stroke centers (n=16). BAO was defined as angiographically (CTA, MRI or conventional angiography) confirmed occlusion of the basilar artery. Baseline parameters and therapeutic procedures were recorded. One-year follow-up was conducted prospectively. Results— Differences in baseline parameters were not statistically significant. Time from onset to first angiography was significantly longer in patients with secondary transfer (mean: 355±93 minutes versus 222±198 minutes; P <0.01), mainly attributable to transfer duration (mean:156±73 minutes). In-hospital mortality (22% versus 75%; P <0.01) and 1-year-mortality (30% versus 81%; P <0.01) were lower for patients with direct admission to stroke centers. Fifty-two percent of directly admitted patients versus 13% of patients with secondary transfer ( P =0.02) were living at home after 1 year. Conclusions— BAO patients who were admitted primarily to community hospitals had a worse prognosis. Patients with typical symptoms should have direct access to stroke centers, or may need bridging therapies.