Background: Bleeding during hepatic surgery is associated with prolonged hospitalization and increased morbidity and mortality. The Veriset haemostatic patch is a topical haemostat comprised of an absorbable backing made of oxidized cellulose and self-adhesive hydrogel components. It is designed to achieve haemostasis quickly and adhere to tissues without fixation. Methods: A prospective, randomized, multicentre, single-blinded study (n = 50) was performed to compare the use of a Veriset haemostatic patch with a fibrin sealant patch (TachoSil (R)) (control) in the management of diffuse bleeding after hepatic surgery. Patients were randomized following the confirmation of diffuse bleeding requiring the use of a topical haemostat. Time to haemostasis was assessed at preset intervals until haemostasis was achieved. Results: Both groups were similar in comorbidities and procedural techniques. The median time to haemostasis in the group using the Veriset haemostatic patch was 1.0min compared with 3.0min in the control group (P