Association for Research in Vision and Ophthalmology, Investigative Ophthalmology & Visual Science, 8(55), p. 5382
Full text: Download
Blindness in sickle cell disease is most debilitating and unfortunately common. Herein, we present for the first time, the retinal pigment epithelium as a novel target for fetal hemoglobin induction and therapeutic management of sickle cell retinopathy, and monomethylfumarate as a new and potent therapy for use in this purpose.