Oxford University Press (OUP), Bioinformatics, 12(30), p. i165-i174
DOI: 10.1093/bioinformatics/btu265
Hans Publishers, Biophysics, 3(55), p. 160-163
Full text: Download
Motivation: Metabolic pathway analysis is crucial not only in metabolic engineering but also in rational drug design. However, the biosynthetic/biodegradation pathways are known only for a small portion of metabolites, and a vast amount of pathways remain uncharacterized. Therefore, an important challenge in metabolomics is the de novo reconstruction of potential reaction networks on a metabolome-scale.