Dissemin is shutting down on January 1st, 2025

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Oxford University Press (OUP), Bioinformatics, 12(30), p. i165-i174

DOI: 10.1093/bioinformatics/btu265

Hans Publishers, Biophysics, 3(55), p. 160-163

DOI: 10.2142/biophys.55.160

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Metabolome-scale prediction of intermediate compounds in multistep metabolic pathways with a recursive supervised approach

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Data provided by SHERPA/RoMEO

Abstract

Motivation: Metabolic pathway analysis is crucial not only in metabolic engineering but also in rational drug design. However, the biosynthetic/biodegradation pathways are known only for a small portion of metabolites, and a vast amount of pathways remain uncharacterized. Therefore, an important challenge in metabolomics is the de novo reconstruction of potential reaction networks on a metabolome-scale.