Tim Somervaille - Dissemin

2015 Tim D. D. Somerville, Daniel H. Wiseman, Gary J. Spencer, Xu Huang, James T. Lynch, Hui Sun Leong, Emma L. Williams, Edmund Cheesman, Tim C. P. Somervaille

Frequent Derepression of the Mesenchymal Transcription Factor Gene FOXC1 in Acute Myeloid Leukemia

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Daniel H. Wiseman, Struys EA Wilks DP Clark CI Dennis MW Jansen EE Salomons GS Somervaille T.-C. Wiseman Dh, E. A. Struys, D. P. Wilks, C. I. Clark, Michael W. Dennis, E. E. W. Jansen, G. S. Salomons, Tim C. P. Somervaille

Direct comparison of quantitative digital PCR and 2-hydroxyglutarate enantiomeric ratio for IDH mutant allele frequency assessment in myeloid malignancy

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K. Korfi, A. Mandal, S. J. Furney, D. Wiseman, T. C. P. Somervaille

, R. Marais, Mandal A Furney SJ Wiseman D Somervaille TC Marais R. Korfi K.

A personalised medicine approach for ponatinib-resistant chronic myeloid leukaemia

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Tamara Maes, Cristina Mascaró, Alberto Ortega, Serena Lunardi, Filippo Ciceri, Tim C. P. Somervaille

, Carlos Buesa

KDM1 histone lysine demethylases as targets for treatments of oncological and neurodegenerative disease

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2014 Daniel H. Wiseman, Helen F. Small, Deepti P. Wilks, Ian D. Waddell, Michael W. Dennis, Donald J. Ogilvie, Tim C. P. Somervaille

Elevated plasma 2-hydroxyglutarate in acute myeloid leukaemia: association with theIDH1SNP rs11554137 and severe renal impairment

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This paper is available in a repository.

Julian G. Jude, Gary J. Spencer, Xu Huang, Tim D. D. Somerville, David R. Jones, Nullin Divecha, Tim C. P. Somervaille

, Spencer GJ Huang X Somerville TD Jones DR Divecha N Somervaille T.-C. Jude Jg

A targeted knockdown screen of genes coding for phosphoinositide modulators identifies PIP4K2A as required for acute myeloid leukemia cell proliferation and survival.

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2013 James T. Lynch, Mark J. Cockerill, James R. Hitchin, Daniel H. Wiseman, Tim C. P. Somervaille

CD86 expression as a surrogate cellular biomarker for pharmacological inhibition of the histone demethylase lysine-specific demethylase 1

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Xu Huang, Gary J. Spencer, James T. Lynch, Filippo Ciceri, Tim D. D. Somerville, Tim C. P. Somervaille

, Spencer GJ Lynch JT Ciceri F Somerville TD Somervaille T.-C. Huang X.

Enhancers of Polycomb EPC1 and EPC2 sustain the oncogenic potential of MLL leukemia stem cells

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Brigit F. Greystoke, Xu Huang, Deepti P. Wilks, Shayne Atkinson, Tim C. P. Somervaille

, Huang X Wilks DP Atkinson S Somervaille Tc Greystoke Bf

Very high frequencies of leukaemia-initiating cells in precursor T-acute lymphoblastic leukaemia may be obscured by cryopreservation

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Daniel H. Wiseman, Greystoke BF Somervaille Tcp-C. Wiseman Dh, Brigit F. Greystoke, Tim C. P. Somervaille

The variety of leukemic stem cells in myeloid malignancy.

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Daniel J. White, Unwin RD Bindels E Pierce A Teng HY Muter J Greystoke B Somerville TD Griffiths J Lovell S Somervaille TC Delwel R Whetton AD Meyer S. White Dj, Richard D. Unwin, Eric Bindels, Andrew Pierce, Hsiang-Ying Teng, Joanne Muter, Brigit F. Greystoke, Tim D. D. Somerville, John Griffiths, Simon Lovell, Tim C. P. Somervaille

, Ruud Delwel, Anthony D. Whetton, Stefan Meyer and 1 other authors

Phosphorylation of the Leukemic Oncoprotein EVI1 on Serine 196 Modulates DNA Binding, Transcriptional Repression and Transforming Ability

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J. T. Lynch, Tim D. D. Somerville, Gary J. Spencer, Xu Huang, Tim C. P. Somervaille

, Somerville TD Spencer GJ Huang X Somervaille Tc Lynch Jt

TTC5 is required to prevent apoptosis of acute myeloid leukemia stem cells

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Mark S. Williams, Nisha Ali, Daisuke Nonaka, Adrian J. Bloor, Tim C. P. Somervaille

Fatal invasive aspergillosis of the larynx

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Zena Salih, Jim Cavet, Mike Dennis, Samar Kulkarni, Tim C. P. Somervaille

, Adrian Bloor, Cavet J Dennis M Somervaille TC Bloor A Kulkarni S. Salih Z.

Prognostic factors for mortality with fungal blood stream infections in patients with hematological and non-hematological malignancies.

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