92 papers found
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Carvacrol reduces adipogenic differentiation by modulating autophagy and ChREBP expression
Nobel committee honors tumor immunologists
Metformin triggers apoptosis in PEL cells and alters bortezomib-induced Unfolded Protein Response increasing its cytotoxicity and inhibiting KSHV lytic cycle activation
Apigenin, by activating p53 and inhibiting STAT3, modulates the balance between pro-apoptotic and pro-survival pathways to induce PEL cell death
Oxidant species are involved in T/B-mediated ERK1/2 phosphorylation that activates p53-p21 axis to promote KSHV lytic cycle in PEL cells
p53-Dependent PUMA to DRAM antagonistic interplay as a key molecular switch in cell-fate decision in normal/high glucose conditions
Histone deacetylase inhibitors VPA and TSA induce apoptosis and autophagy in pancreatic cancer cells
Quercetin induces apoptosis and autophagy in Primary Effusion Lymphoma cells by inhibiting PI3K/AKT/mTOR and STAT3 signaling pathways
Reactivation of mutant p53 by capsaicin, the major constituent of peppers
Apoptosis as anticancer mechanism: function and dysfunction of its modulators and targeted therapeutic strategies
Klionsky et al 2016 Guidelines for autophagy
2016Autophagy
Concomitant reduction of c-Myc expression and PI3K/AKT/mTOR signaling by quercetin induces a strong cytotoxic effect against Burkitt's lymphoma
Mutant p53 proteins alter cancer cell secretome and tumour microenvironment: involvement in cancer invasion and metastasis
High glucose and hyperglycemic sera from type 2 diabetic patients impair DC differentiation by inducing ROS and activating Wnt/β-catenin and p38 MAPK
Hyperglycemia triggers HIPK2 protein degradation
The beneficial effect of Zinc(II) on low-dose chemotherapeutic sensitivity involves p53 activation in wild-type p53-carrying colorectal cancer cells
Zn(II)-curc targets p53 in thyroid cancer cells
High glucose dephosphorylates serine 46 and inhibits p53 apoptotic activity
SLC25A1, or CIC, is a novel transcriptional target of mutant p53 and a negative tumor prognostic marker
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